AutoNessus automates regular Nessus scans and provides delta reporting. It reduces the analysis time for subsequent scans of the same infrastructure by only reporting delta findings.
Version 1.3.2 was released today and it brings Nessus 4 compatibility as well as various bug fixes.
Here’s a screencast of how AutoNessus works:
Update (February 2016): Multimedia file removed, as it was using Adobe Flash.